Gay and bisexual men who reported engaging in
chemsex (the use of specific drugs to enhance or facilitate sex) were
five times more likely to be newly diagnosed with HIV, nine times more
likely to be diagnosed with hepatitis C and four times more likely to be
diagnosed with a sexually transmitted infection (STI) during a 13-month
follow-up period, according to London data published this week in HIV Medicine.
“This is the first published study to demonstrate a significant
association between chemsex disclosure and new HIV diagnosis,” said Dr
Mark Pakianathan and colleagues at St George’s University Hospital,
London. Clinicians and public health officials should use the findings
to identify a population particularly vulnerable to HIV acquisition who
could be targeted for pre-exposure prophylaxis (PrEP) and other
prevention interventions, they say.
(A previous aidsmap.com article reported on harms associated with chemsex.)
Their ages ranged from 14 to 82 years, but the median was 34. Just
under a third were born outside the UK and the cohort was ethnically
diverse.
Currently engaging in chemsex was reported by 286 men (16.5% of all men).
Drugs most commonly used for chemsex were mephedrone (198 men),
GHB/GBL (152 men), crystal methamphetamine (126 men), cocaine (54 men),
other amphetamines (36 men) and ketamine (22 men). Of note, the St
George’s researchers used a wider definition of chemsex than some other
groups, who define it as only the use of the first three drugs in a
sexual context.
Men often used more than one drug at the same time. Injecting drug use was reported by 74 men.
Whereas 1.8% of men who did not report chemsex had a new HIV
diagnosis during 2014 or 2015, this was the case for 8.6% of men who
were involved in chemsex. In multivariate analysis (which took into
account a range of other factors which influence HIV infection), chemsex
was associated with a fivefold increase in the risk of HIV infection
(adjusted odds ratio 5.1, 95% confidence interval 2.6-10.1).
The researchers comment that chemsex sessions may last several days
and involve mucosally traumatic sex with multiple partners. Given the
high incidence of HIV in this population, sexual partners who met at
chemsex parties may be men who have very recently acquired HIV, have not
been diagnosed and have an extremely high viral load.
A new diagnosis of hepatitis C occurred in 0.2% of men who did not
report chemsex and 2.8% of men who did (eleven men in total). In
multivariate analysis, this amounts to a ninefold increase in risk
(adjusted odds ratio 9.2, 95% confidence interval 2.3-36.3).
Similarly, diagnoses of STIs were elevated in men involved in
chemsex. This was true for all STIs (adjusted odds ratio 3.5), rectal
STIs (4.5) and acute bacterial STIs (3.9).
Gay and bisexual men attending sexual health services should be
assessed for chemsex participation, the researchers say. “Disclosure
should prompt health promotion, harm minimization and wellbeing
interventions.”
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